CompletedPhase 2/3

Management of Pain Post Hepatectomy : Infiltration of Local Anesthetics Versus Continuous Spinal Analgesia .

France186 participantsStarted 2015-05-20

Plain-language summary

Analgesia in liver surgery is a challenge, postoperative coagulopathy risk raises fears an epidural haematoma formation following the epidural analgesia, "gold standard" in major abdominal surgery. The spinal analgesia and/or continuous wound infiltration of local anesthetics constitute so an alternative. The study will compare the continuous infiltration of local anesthetics and rachianalgesia in terms of decreased postoperative morphine consumption and incidences of chronic postoperative pain at 3 and 6 months after hepatic surgery compared to the control group.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Surgery of hepatic resection by first under costal. * Patient classified ASA 1 to 3. * Information, signed and informed consent Exclusion Criteria: * Patients classified ASA 4 or 5. * Allergy or intolerance to any of the products used in the protocol. * Emergency surgery, palliative surgery, surgical recovery. * History of chronic pain requiring the regular use of analgesics, especially opioids. * History of drug misuse. * Inability to understand and / or use the patient's self-controlled morphine pump. * Known history of psychiatric disorders or current psychotropic treatment (excluding benzodiazepine monotherapy) * Additive behavior with respect to alcohol or non-weaned psychodysleptic substances * Pregnant Woman or Breastfeeding

What they're measuring

Morphine Consumption

Timeframe: During the first 24 hours post operative

Trial details

NCT IDNCT03238430

SponsorUniversity Hospital, Lille

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2019-05-25