Assessment of Valproate on Ethanol Withdrawal

Inclusion Criteria: * Admission to Trauma Services * Heavy drinkers based on social history * Men \<65 years: \> 4 drinks per day or 14 per week * Women: \> 3 drinks per day or 7 drinks per week * All adults \>65 years: \> 3 drinks per day or 7 drinks per week * Moderate or severe alcohol use disorder based on social history and DSM-5 criteria * Moderate: Presence of 4-5 symptoms based on social history * Severe: Presence of 6 symptoms based on social history Exclusion Criteria: * Intubated patients * Glasgow Coma Score \<8 * Grade IV liver laceration or greater * Child-Pugh Class B or greater, history of cirrhosis, or cirrhosis identified by radiographic imaging upon admission * Transaminase (AST/ALT) elevation of ≥ 2x normal * Anticipated admission less than 72 hours * Levetiracetam administration for seizure prophylaxis secondary to a traumatic brain injury * Patient with VPA as home medication * Known allergy to VPA * Patients with pre-existing blood dyscrasias, i.e. thrombocytopenia (platelet count \< 50,000, etc) * Inability to obtain social history from patient, surrogate, family member or an individual deemed to be knowledgeable about the patient's social history * Pregnancy