CompletedNot Applicable

Prevalence and Characteristics of Fabry Disease (FD) in Patients With Stroke or Small Fiber Neuropathy

France379 participantsStarted 2018-03-12

Plain-language summary

FD is pan-ethnic. Its reported annual incidence of 1 in 100,000 may underestimate the true prevalence of the disease. Indeed, recently, in addition with affected males FD developing a "classic" phenotype, " cardiac variant " and " renal variant " have been reported for FD patients with predominant or exclusive cardiac or renal involvement. " Neurologic variant " could exist. Nervous system can be affect by FD leading to cerebrovascular diseases (ischemic or haemorrhagic strokes, TIA (Transient Ischemic Attacks) or peripheral neuropathy (acroparesthesias and pain). Aims will be to determine the prevalence of Fabry disease in patients with stroke or small fiber neuropathy, and their characteristics

Who can participate

Age range18 Years – 60 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * patient over 18 yo and under 60 yo * diagnosed with a TIA / stroke (ischemic and haemorrhagic strokes) based on clinical evaluation and MRI * diagnosed with small fibers neuropathy (SFN) with normal nerve conduction studies in conventional electrophysiology Exclusion Criteria: * patients over 60 yo

What they're measuring

frequency of FD in a cohort of stroke patients

Timeframe: at the end of the study (an average of 2 years)

Trial details

NCT IDNCT03230149

SponsorAssistance Publique - Hôpitaux de Paris

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2021-12-24

View on ClinicalTrials.gov More Fabry Disease trials