Software Monitoring of Treatment Related Toxicities in Advanced Renal Cell Carcinoma

Inclusion Criteria: * Diagnosis of histologically confirmed renal cell carcinoma of any subtype with either pathological or radiographic evidence of metastatic disease * Greater than 18 years of age * A participating Wilmot Cancer Center oncologist has determined that candidate should be started on either oral targeted therapy or immunotherapy for treatment of their advanced RCC; this can be for first-line or any subsequent line therapy * Able to provide written informed consent * Proficient in the English language and self-reports as literate * Must have an active email address or access to a smart device on which text messages can be received Exclusion Criteria: * Women cannot be breast-feeding * Does not have regular access to the internet * Unable to come to the Wilmot Cancer Center for appointments every 3-4 months for routine visits with their primary oncologist * Subjects who were on the study previously will not be allowed to re-enroll in the event of a treatment change