CompletedNot Applicable

Propofolsleep - A Study on Cardiopulmonary and Pharyngeal Reactions While Drug Induced Sleep Endoscopy (DISE)

Germany20 participantsStarted 2017-08-22

Plain-language summary

While Drug Induced Sleep Endoscopy (DISE) in patients with obstructive sleep apnea syndrome (OSAS) apnea and hypopnea occur. Because of the induced phases of apnea in a controlled setting it is possible to evaluate the related pathophysiology of apnea. We plan to correlate the Patient State Index (PSI) and other physiologic parameters with phases of apnea and hypopnea.

Who can participate

Age range18 Years

SexALL

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Inclusion Criteria: * informed written consent * age of 18 years or older * no participation in other prospective interventional studies * OSAS with a polysomnographic shown AHI (apnea-hypopnea-index) of 15/h or more Exclusion Criteria: * no written informed consent * allergies against study medication * ASA (american society of anesthesiologists) class 4 or higher * neurodegenerative CNS (central nerve system) or muscle diseases * pregnant or breastfeeding patients * 25 % or more central or mixed apneas in polysomnography

What they're measuring

PSI

Timeframe: Duration of surgery (an average of 2 hours)

Trial details

NCT IDNCT03224936

SponsorCharite University, Berlin, Germany

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2019-10-30

View on ClinicalTrials.gov More Sleep Apnea, Obstructive trials