UnknownNot Applicable

Cyclosporin A Therapy in Childhood Nephrotic Syndrome

50 participantsStarted 2018-04-01

Plain-language summary

Nephrotic syndrome (NS) is among the most common pediatric kidney diseases and is defined as massive proteinuria (\>40 mg/m2/h or urine protein to creatinine ratio \>2 g/g) leading to hypoalbuminemia (\<2.5 g/dL), edema, and hyperlipidemia. 60-70 % of patients present prior to age of 6 years

Who can participate

Age range1 Year – 18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * The study will include all children (on cyclosporine therapy for treatment of Steroid dependent or Steroid resistant nephrotic syndrome ) who present to Nephrology Unit , and clinic at Assiut University Children Hospital during one year duration. Exclusion Criteria: * children with adequate response to steroid therapy and without relapses or resistance to steroid therapy

What they're measuring

evaluation of nephrotic state of each patient for evaluation of efficacy of cyclosporin A therapy

Timeframe: one year

evaluation of side effects of cyclosporin A

Timeframe: one year

Trial details

NCT IDNCT03219684

SponsorAssiut University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2019-04-01

Contact for this trial

Muhammed Mahrous, MD

01003486595 eltellawy270@hotmail.com

View on ClinicalTrials.gov More Steroid Dependent and Steroid Resistent Nephrotic Syndrome trials