Normative Database for HR-pQCT-Based Radius and Tibia Strength

Inclusion Criteria: * Healthy volunteers aged 20 years or older living in Switzerland * Written informed consent Exclusion Criteria: * Psychological disorder or dementia in order to understand the informed consent and be able to fill the FRAX questionnaire * Implant or a fracture at the DXA and HR-pQCT measurement sites * Inability to keep the extremities still for the few minutes of an HR-pQCT examination (e.g. Parkinson disease or spastic syndrome) * History of low trauma fracture * Known pregnancy or lactating women * History of hysterectomy and/or ovariectomy * Known metabolic bone disorders, such as osteogenesis imperfecta, Paget's disease or sclerosteosis (osteopenia or idiopathic osteoporosis are not exclusion criteria) * Ever use of one or more of the following bone active substances: bisphosphonates, RANKL-inhibitors (DENOSUMAB), selective estrogen receptors (SERMS) or parathormone/teriparatide * Ever use of oral glucocorticoids during more than 3 months or currently taking glucocorticoids