Glycogen Storage Disease Breath Test Study

Inclusion Criteria: Experiment 1 * Healthy adults 19 - 35 years of age * Adults who have no medical conditions * Adults who currently free from any concurrent illness such as fever or cold Experiment 2 Healthy Controls: * Healthy children 5 - 18 years of age * Healthy adults 19 - 35 years of age * Children and adults who have no medical conditions * Children and adults who currently free from any concurrent illness such as fever or cold Subjects with GSD I: * Children 5 - 18 years of age who are diagnosed with GSD I * Adults 19 - 35 years of age who are diagnosed with GSD I * Clinically stable children and adults with GSD I with no concurrent illness such as fever, cold, vomiting or diarrhea * Children and adults with GSD I who have had the clinical decision made to start the extended release waxy maize cornstarch Glycosade® Exclusion Criteria: Experiment 1 * Healthy adults above age 35 years * Adults who have a history of cardiovascular disease, liver or kidney disease, metabolic, pulmonary, gastrointestinal or endocrine disorder * Healthy adults but are currently ill with a fever, cold, vomiting or diarrhea * Healthy adults with claustrophobia * Healthy adults currently smoking or consuming more than one drink containing alcohol each day * Adults currently or recently taking medication or antibiotics Experiment 2 Healthy Controls: * Healthy children under age 5 years * Healthy adults above age 35 years * Children and adults who have a history of cardiovascular …