Comparison of Hydro-dissection Versus Ultrasonic Aspirator in Division of Liver Parenchyma in Laparoscopic Resection

Inclusion Criteria: * Patients with benign lesions (hemangioma, focal nodular hyperplasia \[FNH\], hepatocellular adenoma, biliary cystadenoma, hydatid echinococcosis \[only with total pericystectomy\]) and malignant tumors (colorectal cancer metastases in the liver \[CRLM\], hepatocellular carcinoma \[HCC\], intrahepatic cholangiocellular carcinoma, gallbladder cancer T1b-3NxMo without invasion into bile ducts and adjacent organs), which involves laparoscopic segmental or major resection of the liver. * Gender: both, male and female * Minimum age 18 years * Maximum age: 80 years * ASA physical status I-IV * BMI up to 40 kg/m2 * No simultaneous extrahepatic intra-abdominal procedures (bile duct resection, colon resection, partial duodenum resection) * Total bilirubin up to 100mmol/l if jaundice presents in non-cirrhotic patients * If cirrhosis is present, class A and B according to CTP score Exclusion Criteria: * • Difficulty index \> 12 points (see below) * Tumor invasion of IVC or portal trunk (necessity of vascular reconstruction) * Repeated liver resection before laparoscopic resection (the single resection before is not a contraindication) * Simultaneous extra-hepatic intra-abdominal procedures (bile duct resection, colon resection etc.) * Age under 18 years * Age above 80 years * ASA physical status \>IV * BMI \> 40 kg/m2 * Total bilirubin \>100mmol/l if jaundice presents in non-cirrhotic patients * If cirrhosis is present, class C according to CTP…