Collection of Immunology Specimens From Patients With Cancer or Blood Disorders, and Healthy Volu… (NCT03207854) | Clinical Trial Compass
RecruitingNot Applicable
Collection of Immunology Specimens From Patients With Cancer or Blood Disorders, and Healthy Volunteers
United States625 participantsStarted 2017-04-12
Plain-language summary
This research trial collects and stores blood, tissue, and bone marrow specimens from patients with cancer or blood disorders, and healthy volunteers to study the immune system in a variety of different types of experiments, as well as associated clinical data as appropriate, focused on understanding mechanisms of immunotherapy.
Who can participate
Age range19 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* All patients known to have cancer, an immune-mediated hematologic diagnosis, or a healthy normal volunteer
* Definition of immune-mediated hematologic diagnosis: diagnoses for which immune dysfunction and/or immune system directed therapy (eg. aplastic anemia, autoimmune hemolytic anemia, immune thrombocytopenic purpura \[ITP\], etc.) are involved
* Definition of healthy normal volunteer: persons lacking diagnoses of any type of cancer, diabetes, cardiovascular diseases, non-hematologic autoimmune disease (eg. systemic lupus erythematosus \[SLE\], rheumatoid arthritis \[RA\], Crohn's disease) and not taking any immunosuppressive medications
* Patients must have been seen in the Norris Hospital and outpatient clinics, or the Los Angeles County (LAC)-University of Southern California (USC) Medical Center or outpatient clinics; healthy volunteers can be recruited without any physician visit appointments since their labs are strictly for clinical research and not for personal health issues unrelated to the project
Exclusion Criteria:
* Unable to give informed consent to specimen collection
* Known human immunodeficiency virus (HIV) positive status
* Persons taking any type of immunosuppressive medication are excluded from participating as healthy normal volunteers
* Any patient for whom specimen collection is judged to be unsafe (for example, for patients unable to establish venous access)
What they're measuring
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Sample collection for immunology studies from patients with cancer or blood disorders, and healthy volunteers