Direct Peritoneal Resuscitation in Gastroschisis

Inclusion Criteria: * Diagnosis of Gastroschisis * Male or Female, any ethnicity * Neonates \[0-27 days as defined by the Age Classification in the ICH E-11\] Exclusion Criteria: * Primary gastroschisis repair * Vanishing gastroschisis * Encapsulating peritoneal sclerosis * Infants \< 2 kg and \< 34 weeks gestation * Infants \> 12 hours at enrollment * Severe hypotension, defined as either: * Mean arterial blood pressure (MAP) \< gestational age in weeks, or * Systolic blood pressure (BP) \< 45 or diastolic BP \< 20 * Severe Hypertension defined as Systolic BP \> 90 or diastolic \> 60 * Culture-positive sepsis * Known or strongly suspected inborn errors of metabolism * Significant cardiac disorders, including cyanotic congenital heart disease, ductal-dependent congenital heart disease, and critical congenital heart disease (lesions requiring surgery or catheter-based intervention in the first year of life) * Respiratory failure, defined as any requirement of positive pressure ventilation at the time of enrollment, or FiO2 \> 50% * Any other condition, that, in the opinion of the investigator, might interfere with the safe conduct of the study or place the subject at increased risk * Lactic acidosis with at least one or more of the following: * Characterized by increased blood lactate levels (\> 5 mmol/L) on two occasions at least 6 hours apart * Severe metabolic acidosis with an arterial pH ≤ 7.0 * Bicarbonate \< 14 or CO2 \< 12 * Base excess of \> -10 mEq/L …