CompletedNot Applicable

Inflammatory Stress Response in Pediatric Inguinal Hernia Repair

Croatia32 participantsStarted 2017-05-01

Plain-language summary

Today there are various surgical techniques for inguinal hernia. In this study, investigators want to compare the ''PIRS'' operating technique laparoscopy and modified "Marcy" operating technique with open inguinal access. Investigators would compare both groups to find out witch one does the lesser inflammatory stress response on the organism.

Who can participate

Age range3 Years – 7 Years

SexMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * male children with inguinal hernia at age of 3 to 7 * one-sided inguinal hernia Exclusion Criteria: * Female children * recurrent hernia * bilateral hernia * age less than 3 y, more than 7 y * any general inflammatory process, illness * intraoperative complications which may interfere with inflammatory stress response

What they're measuring

Change in inflammatory stress response (IL6)

Timeframe: 3 measurements: preoperative, 24 hours after and 6 days after surgery

Change in inflammatory stress response (CRP)

Timeframe: 3 measurements: preoperative, 24 hours after and 6 days after surgery

Change in inflammatory stress response (TNF alpha)

Timeframe: 3 measurements: preoperative, 24 hours after and 6 days after surgery

Change in inflammatory stress response (Leukocytes WBC)

Timeframe: 3 measurements: preoperative, 24 hours after and 6 days after surgery

Trial details

NCT IDNCT03203343

SponsorUniversity Hospital of Split

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2018-06-01

View on ClinicalTrials.gov More Inguinal Hernia, Indirect trials