The Lung Screening, Tobacco and Health Project (NCT03200236) | Clinical Trial Compass
CompletedPhase 3
The Lung Screening, Tobacco and Health Project
United States1,114 participantsStarted 2017-05-03
Plain-language summary
The purpose of this study is to compare intensive telephone counseling (ITC) plus the nicotine patch vs. standard telephone counseling plus the nicotine patch (Usual Care; UC) among current smokers undergoing lung cancer screening. Smoking-related outcomes will be examined at three, six and twelve months post-randomization.
Who can participate
Age range
50 Years – 80 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Have a \>20-pack year smoking history (i.e., smoked at least a pack a day for 20 years)
* Current smokers, regardless of number smoked per day
* Can be smoking cigarettes, cigarillos, or little cigars
* English- or Spanish-speaking
* Ability to provide meaningful consent
* Have registered for CT lung cancer screening at one of our five participating lung screening sites (for enrollment) and have completed CT lung cancer screening (for subsequent follow-ups).
* Current smokers are eligible to participate regardless of prior lung cancer screening or prior cessation treatment. Smokers not yet ready to quit will be encouraged to participate.
Exclusion Criteria:
* Previously diagnosed with lung cancer
* Diagnosed with lung cancer during the study (although still eligible to receive free telephone counseling and nicotine replacement)
* At the T1 assessment when randomization occurs, individuals who have been quit for 8+ days will not be randomized. We will request that they participate in follow-up assessments of smoking status at 3-, 6- and 12-months.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is completed — does that mean results are already available, and if so, what did they find about whether lung cancer screening visits can actually help people quit smoking?
2Since this was a Phase 3 trial measuring smoking cessation rates at 3, 6, and 12 months, how do those quit rates compare to what I might expect from standard smoking cessation programs my doctor could refer me to right now?
3The trial focused on people who were already getting lung cancer screening — does my doctor think combining a quit-smoking program with my own screening visits would be a realistic approach for me given my current smoking history?
4Because this trial is completed and no longer enrolling, are there similar active studies or evidence-based cessation programs that grew out of this kind of research that my doctor could connect me with?
5Given that this trial tracked participants for up to a full year to measure quitting success, what does my doctor think is the most realistic timeline and support plan I'd need to actually sustain quitting, based on what studies like this have shown?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Smoking cessation rate at 3-months post-randomization
Timeframe: Self-report measured at 3-months post-randomization; biochemical verification measured at 3-months.
2
Smoking cessation rate at 6-months post-randomization
Timeframe: Self-report measured at 6-months post-randomization; biochemical verification measured at 6-months.
3
Smoking cessation rate at 12-months post-randomization
Timeframe: Self-report measured at 12-months post-randomization; biochemical verification measured at 12-month assessment;