TerminatedNot Applicable

Linking Epidermal Barrier Function With Anti-Oxidant Defense Mechanisms in Skin Conditions

Stopped: Investigator left university

United States100 participantsStarted 2017-08-04

Plain-language summary

Investigators will sample the skin and blood of patients with chronic skin conditions (including but not limited to atopic dermatitis (AD), contact dermatitis, hidradenitis suppurativa (HS), and psoriasis) to study the expression of anti-oxidative enzymes, skin barrier proteins and inflammatory molecules. In patients with atopic dermatitis, investigators will also measure skin barrier function using noninvasive devices. These results will be correlated with the disease severity in atopic dermatitis patients.

Who can participate

Age range18 Years – 99 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: Male and female 18 to 99 years of age. Chronic skin conditions (including but not limited to atopic dermatitis, contact dermatitis, hidradenitis suppurativa, and psoriasis) with at least one active skin lesion Healthy skin (defined no clinical evidence or diagnosis of inflammatory skin conditions) Exclusion Criteria: Subjects who are unable to comply with study procedures.

What they're measuring

Skin barrier function

Timeframe: 1 hour

Skin barrier function

Timeframe: 1 hour

Skin pH

Timeframe: 1 hour

Trial details

NCT IDNCT03198390

SponsorUniversity of Arizona

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2020-05-31

View on ClinicalTrials.gov More Atopic Dermatitis trials