Comparison of Clenpiq vs Golytely Bowel Preparation

Inclusion Criteria: \- Patients who need a colonoscopy while in the hospital (Cleveland Clinic main campus) will be eligible to participate. Exclusion Criteria: * Creatinine clearance less than 30 ml/min * History of heart failure with current shortness of breath at rest causing limited physical activity, arrhythmia, unstable angina or acute myocardial infarction * Small bowel obstruction, ileus or bowel perforation * Dementia or cognitive dysfunction to an extent that they cannot perform the study related documentation or consent to participate in the study. * Gastroparesis * Toxic megacolon or undergoing colonoscopy for decompression * Taking oral tetracyclines, fluoroquinolones, antibiotics, iron, digoxin, chlorpromazine and penicillamine within 2 hours before or 6 hours after administration of Clenpiq or stimulant laxatives within 24 hours * History of prior colorectal surgery * Allergy to any of the ingredients in Clenpiq or golytely * if the procedure is planned in the intensive care unit (ICU)