Brinzolamide/Brimonidine Combination vs Brimonidine 0.2% in the Prevention of IOP Rise After Nd-YAG Laser Capsulotomy

Inclusion Criteria: * patients scheduled to undergo laser posterior capsulotomy due to posterior capsule opacification (PCO) after uneventful phacoemulsification cataract extraction with implantation of posterior chamber intraocular lenses (IOL/PC). Exclusion Criteria: * baseline IOP greater than 21mmHg * glaucomatous eyes, already under treatment with anti glaucomatic medications * intraocular surgery except for uncomplicated cataract surgery * previous photorefractive surgery * active ocular inflammation or infection * patients under systemic administration of medications known to affect IOP * patients with severe respiratory or cardiovascular disease * pregnant or breast feeding women, and individuals with known hypersensitivity or contraindication for administration of the medications tested * a measurement of IOP \> 30 mmHg at any time point of the study, or an increase from baseline \>20 mmHg