Evaluating Bactisure Wound Lavage in Orthopedic Wounds

Inclusion Criteria: * Patient is undergoing I \& D or reoperation (revision) surgery for an infected primary TKA. * Patient is 18 years of age or greater. * Patient is skeletally mature. * Occurs within 30 days of the operation or within 1 year or more if an implant is present * Involves deep soft tissues (e.g., fascia and/or muscle) of the incision * Patient is willing and able to provide written informed consent. * Patient is willing and able to complete scheduled follow-up evaluations as described in the protocol Exclusion Criteria: Patients will be excluded from this study if: * Patient is unwilling or unable to give consent or to comply with the follow-up program. * Known sensitivity or allergic reaction to benzalkonium chloride one or more of the solvent, chelating agent, or buffer in the solution * Multiple (\>1) infected implants * Medically unfit for irrigation \& debridement procedure * Pregnancy * The patient is: * prisoner * mentally incompetent or unable to understand what participation in the study entails * anticipated to be non-compliant.