CompletedPhase 2

AMCPR (Augmented-Medication CardioPulmonary Resuscitation) Trial for OHCA

South Korea110 participantsStarted 2017-12-31

Plain-language summary

The investigators aimed to evaluate the effect of AMCPR (Augmented-Medication CardioPulmonary Resuscitation: administration of additional vasopressin to titrate to arterial diastolic blood pressure over 20 mmHg) on cardiopulmonary resuscitation results and outcomes in out-of-hospital cardiac arrest patients.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * non-traumatic adult out-of-hospital cardiac arrest (OHCA) patients with non-shockable arrest rhythm Exclusion Criteria: * OHCA with terminal illness documented by medical record, under hospice care, with pregnancy, with pre-documented 'Do Not Resuscitate' card * trauma patients * age \< 18 years old * failed arterial line insertion within 6 minutes after randomization * Extracorporeal cardiopulmonary resuscitation * Time interval between arrest and ED arrival \> 60 minutes * ROSC within 6 minutes after ED arrival * Diastolic Blood Pressure \> 20 mmHg during resuscitation

What they're measuring

Sustained return of spontaneous circulation (ROSC)

Timeframe: for 20 minutes after the time that participants had a palpable pulse

Trial details

NCT IDNCT03191240

SponsorAsan Medical Center

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-08-31

View on ClinicalTrials.gov More Out-of-Hospital Cardiac Arrest trials