CompletedPhase 4

Fractional Flow Reserve Derived From Computed Tomography Coronary Angiography in the Assessment and Management of Stable Chest Pain

United Kingdom1,400 participantsStarted 2017-12-04

Plain-language summary

To determine whether, in a population of patients presenting to the rapid access chest pain clinic (RACPC), routine FFRct (Fractional Flow Reserve Computed Tomography) as a default test is superior in terms of resource utilisation when compared to routine clinical pathway algorithms recommended by the National Institute for Health and Care Excellence (NICE)

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Aged over 18 * Primary symptom of chest pain * No contraindication to CTA * Willing and able to provide written informed consent Exclusion Criteria: * Atrial fibrillation of new onset or when rate control has been difficult * Known bigemini/trigeminy * Prior CABG surgery * Allergic to contrast * Advanced renal impairment * Significant valve disease (severe aortic stenosis or regurgitation; severe mitral regurgitation) * Life expectancy \<12 months * Inclusion in another trial without prior agreement with CI

What they're measuring

Resource utilisation

Timeframe: 9 months

Trial details

NCT IDNCT03187639

SponsorUniversity Hospital Southampton NHS Foundation Trust

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2020-06-01

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