TerminatedNot Applicable

Prevalence of Trephined Syndrome After Decompressive Craniectomy

Stopped: departure of one of the investigator

Switzerland41 participantsStarted 2012-01-16

Plain-language summary

Decompressive craniectomy is frequently used to treat increased intracranial pressure or an intracranial mass effect. Trephined Syndrome describes a neurological deterioration, which is attributed to a large craniectomy. The symptomatology is varied but includes headache, aggravation of a hemisyndrome or cognitive disorders, often has an orthostatic component and improves or disappears with cranioplasty. The incidence of Trephined Syndrome has been reported between 7% and 26%. However, it might be underestimated if the course of cognitive functions before and after cranioplasty were insufficiently documented.

Who can participate

Age range14 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients with decompressive craniectomy for intracranial hypertension secondary to stroke, traumatic brain injury or other non-progressive cerebral pathology. Exclusion Criteria: * patients suffering from a rapidly evolving cerebral pathology (e.g. tumor) * patients transferred to other hospitals before cranioplasty or whose follow-up can not be assured.

What they're measuring

Presence of Trephined Syndrome

Timeframe: From patients admission to discharge from rehabilitation (approx. 3 months).

Trial details

NCT IDNCT03186157

SponsorUniversity Hospital, Geneva

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2017-03-31

View on ClinicalTrials.gov More Trephined Syndrome trials