CompletedNot Applicable

Safety of Local Dental Anesthesia in Patients With Cardiac Channelopathies

Brazil31 participantsStarted 2015-05

Plain-language summary

Patients with cardiac channelopathies needing restorative dental treatment will be included in two sessions of the study, using local dental anesthetic: lidocaine 2% with epinephrine and lidocaine 2% without vasoconstrictor. The safety of the use of two cartridges (3.6 mL) will be evaluated. The patients will be their own control and will be assessed by Holter monitoring for 28 hours, blood pressure measurement and anxiety measuring.

Who can participate

Age range6 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients with any channelopathies below, kept on optimal drug therapy, with or without ICD: Brugada Syndrome, Long QT Syndrome and Catecholaminergic Polymorphic Ventricular Tachycardia * Dental caries or unsatisfactory restorations in the mandible, indicating restorative dental treatment Exclusion Criteria: * Patients allergic to lidocaine * Patients undergoing ICD therapy for less than three months * Patients with recurrent syncope in the last three months * Patients with sustained arrhythmias documented for less than 3 months * Have received epinephrine in the last 24 hours

What they're measuring

No sustained ventricular tachycardia

Timeframe: during dental procedures

Trial details

NCT IDNCT03182777

SponsorUniversity of Sao Paulo General Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2018-08

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