Investigating the Cryopreserved Blastocyst's ImplantatiOn Potential After Genetic Screening

Inclusion Criteria: * at least 2 blastocysts suitable for biopsy on day 5 of embryo development remaining after fresh transfer * willing and able to give informed consent * infertility as an indication for IVF/ICSI * first or second IVF/ICSI cycle * patients willing to accept single embryo transfer * BMI range 18 to 35 kg/m2 Exclusion Criteria: * any type of genetic abnormality or family history of genetic abnormality in subject or partner * any other non-study related preimplantation genetic testing * three or more clinical miscarriages (recurrent pregnancy loss, RPL) * recurrent implantation failure (RIF): no positive β-hCG after transfer (fresh IVF/ICSI cycle or frozen) with no less than 6 cleavage stage embryos or no less than 4 blastocysts, all of good quality and of appropriate developmental stage * severe endometriosis * abnormal uterine cavity * cycles requiring surgical sperm recovery procedures, total asthenozoospermia and/or globozoospermia * treatment involving use of donor oocytes or use of gestational carrier