Not Yet RecruitingNot Applicable

ADINA vs. High Flow Nasal Cannula Comparison Study

United States40 participantsStarted 2026-07

Plain-language summary

This study is to evaluate the feasibility of using a pressure limited nasal cannula system instead of a high flow nasal cannula system in the management of premature babies with respiratory distress.

Who can participate

Age range23 Weeks – 40 Weeks

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Neonates admitted to NICU * Weights of 400-500 grams * Requiring oxygen greater than 30% * No evidence of focal lobar consolidation in lung fields Exclusion Criteria: * Intolerance to procedure * gelatinous skin * known allergy to adhesive material * interference with therapy * profound sepsis * pneumonia * unmanaged apnea/bradycardia * known or suspect complex congenital heart disease * severe cleft lip or palate * suspect or proven lethal congenital anomaly * intolerance to the interface used in the devices * inability to secure an appropriate fit of the patient nasal interface * considered non-viable or of uncertain viability * parental refusal.

What they're measuring

Duration of Oxygen Use

Timeframe: From time of randomization until time of discharge from the Neonatal Intensive Care Unit (NICU) up to 100 days.

Trial details

NCT IDNCT03171129

SponsorLoma Linda University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-09

Contact for this trial

Tina Ramirez

909-558-5828 TIRameriz@llu.edu

View on ClinicalTrials.gov More Respiratory Distress Neonatal trials