UnknownNot Applicable

The Effects of Dexmedetomidine on cTnI and GP-BB in Patients Undergoing OPCABG

China40 participantsStarted 2016-02

Plain-language summary

The purpose of this study is to observe the impact of dexmedetomidine on Cardiac Troponin I and Glycogen Phosphorylase Isoenzyme BB in patients undergoing off-pump coronary artery bypass Grafting.

Who can participate

Age range40 Years – 70 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients undergoing off - pump coronary artery bypass grafting * ASA physical status III-IV * Aged 40-70 years * NYHA physical status II-III Exclusion Criteria: * Bradycardia * Atrioventricular block * Echocardiography suggested:LVEF \<40%, LVED\>65mm * Allergic to the drugs

What they're measuring

Change of cardiac troponin I at preoperative, postoperative，and 24 hours after surgery.

Timeframe: At preoperative, postoperative，and 24 hours after surgery.

Change of Glycogen Phosphorylase Isoenzyme BB at preoperative, postoperative，and 24 hours after surgery.

Timeframe: At preoperative, postoperative，and 24 hours after surgery.

Trial details

NCT IDNCT03163693

SponsorGeneral Hospital of Ningxia Medical University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2017-05

View on ClinicalTrials.gov More Coronary Artery Bypass, Off-Pump trials