Combined Application of Remote and Intra-Coronary Ischemic Conditioning in Acute Myocardial Infarction

Inclusion Criteria: * All (male and female) patients, aged over 18, * Presenting within 12 hours of the onset of chest pain, * For whom the clinical decision was made to treat with percutaneous coronary intervention (PCI), * ST segment elevation ≥ 0.2 mV in two contiguous ECG leads, * Written informed consent obtained or oral informed consent certified by a third party. Non inclusion Criteria: * Patients with cardiogenic shock, * Patients with uncontrolled (treated or untreated) hypertension (\> 180/110 mmHg), * Patients with loss of consciousness or confused, * Patients without health coverage, * Patient with any legal protection measure, * Female patients currently pregnant (oral diagnosis) or women of childbearing age who were not using contraception. Exclusion Criteria: Patients with main occlusion localized on : * LAD: distal or ostial segment, * Non dominant RCA / CX: mid or distal segment, * Dominant RCA / CX: distal segment, * Any other arteries apart LAD/CX/RCA; Patients with evidence of coronary collaterals to the risk region (Rentrop score ≥ 2); Patients with an opened (TIMI \> 1) culprit coronary artery on initial admission coronary angiography or a failed PCI (final TIMI=0).