TerminatedPhase 4

Gabapentin on Postoperative Pain Associated With Ureteroscopy and Stents Insertion

Stopped: Insufficient enrollment

United States20 participantsStarted 2018-01-14

Plain-language summary

The study's objective is to determine the efficacy of preoperative gabapentin in relieving postoperative pain, reducing opioid use and improving quality of recovery in subjects undergoing urologic surgery. Investigators hypothesize that subjects receiving gabapentin will have lower pain scores, less opioid consumption and better quality of recovery as compared to subjects who are given a placebo.

Who can participate

Age range18 Years – 75 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age 18 years to 75 years * Patients with obstructive kidney stones undergoing elective ureteroscopy or cystoscopy with Ureteral stent placement Exclusion Criteria: * Age less than 18 or more than 75 years * Acetaminophen allergy * Gabapentin allergy * Hydromorphone allergy * Chronic use of gabapentin * History of chronic pain (Pain for \> than 3 months) * Chronic renal insufficiency (Creatinine \> 1.3) * Seizure disorder * Psychiatric disorders (medically treated) * Chronic use of anticonvulsants, antidepressants, antipsychotics (use \> 3 months) * Antacids ingested within 2 hours prior to surgery * History of gastric or duodenal ulcer * Pregnant or lactating * Inability to communicate in English

What they're measuring

48 Hours Morphine Equivalents Consumed.

Timeframe: Up to 48 hours after surgery

Trial details

NCT IDNCT03151746

SponsorNorthwestern University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-12-02

Results submitted2022-06-28

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