Lesion Detection Assessment in the Liver: Standard vs Low Radiation Dose Using Varied Post-Proces… (NCT03151564) | Clinical Trial Compass
Active — Not RecruitingNot Applicable
Lesion Detection Assessment in the Liver: Standard vs Low Radiation Dose Using Varied Post-Processing Techniques
United States146 participantsStarted 2017-05-09
Plain-language summary
To compare 2 different image creation/processing techniques during a standard CT scan in order to "see" problems in the liver and learn which method provides better image quality. The techniques use new artificial intelligence software to decrease image noise, which helps the radiologist to evaluate.
Who can participate
Age range
18 Years – 90 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. Patient must be \>/= 18 years of age and \</=90 years of age
. Men and non-pregnant women
. Pathology proven diagnosis of colon or colorectal carcinoma
. Liver metastases on most recent CT examination
. Standard of care CT abdomen examination planned WITH IV contrast
Exclusion criteria
. Patients cannot give informed consent
. Patients cannot undergo CT examination
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial compares standard radiation dose CT scans to lower radiation dose CT scans for detecting liver metastases — given my specific situation with colorectal cancer, would a lower-dose imaging approach still be accurate enough to catch any spread to my liver?
2Since this study is 'active but not recruiting,' I can't join it, but could the post-processing techniques being tested here — like image enhancement methods that compensate for lower radiation — already be available at this hospital for my imaging?
3The trial is measuring how accurately metastases are detected under different scanning conditions — does my care team currently use the most up-to-date image processing tools when reading my liver CT scans, and how confident are they in the detection accuracy?
4If reducing radiation dose during CT scans is being studied as a viable option, is there any reason my follow-up liver imaging couldn't use a lower radiation protocol, especially if I'll need repeated scans over time?
5Are there other imaging options — like MRI — that my doctor would recommend comparing against CT for monitoring liver metastases, given that this trial focuses only on CT-based detection methods?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.