CompletedNot Applicable

Kinetics of Serum β-D-glucan During Peritonitis With Candida in Resuscitation

France70 participantsStarted 2018-05-01

Plain-language summary

Intraabdominal fungal infections with Candida are constantly increasing. Their diagnosis and treatment is difficult. Morbidity and mortality are high. Β-D-Glucan has been proposed as a marker of systemic fungal infection in candidemia. Moreover, its kinetics is associated with therapeutic success. On the other hand, there are no data on intraabdominal infections that are much more frequent. The objective of the study is to evaluate the initial levels of β-D-glucan and its daily kinetics during the treatment of fungal peritonitis in resuscitation compared to a control group with a yeast-free peritonitis.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Major Patient (age ≥ 18 years) * Community or associated peritonitis, operated and hospitalized in resuscitation * Affiliation to a social security scheme Exclusion Criteria: * Allergy known to echinocandins * Dying Patient * Limitation of care * Predictable duration of follow-up ≤ 10 days * Transfusion within 3 months * Patient minor, patient under guardianship or curatorship

What they're measuring

Blood determination of serum β-D-glucan kinetics in patients with peritonitis

Timeframe: 28 days

Trial details

NCT IDNCT03140748

SponsorCentre Hospitalier Universitaire, Amiens

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-08-22

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