Candida Host Defense Response After Septic Shock in the Critically Ill

Inclusion Criteria: Age \> = 18 years * The patients in toxic shock defined according to the Bone criteria * Informed consent of the patient or his reliable person (poursuit consent in this case). Possibility of inclusion according to the emergency procedure with the obligation of research for the consent with the reliable person and with the patient. * Obligation of membership or beneficiary to have a national insurance Exclusion Criteria: * Pregnant or breast-feeding women according to the article L1121-5 of the CSP * Vulnerable people according to the article L1121-6 of the CSP 9358 \_ " * Neutropénie 500 / mm3 * Infection by the HIV, the hepatitis C or B active column * Biotherapics (anti-CD20, anti-TNFa, anti-IL-6) * Treatments immunosuppresseurs (methotrexate, azathioprine, cyclophosphamide, mycophenolate mofétil, cyclosporine, tacrolimus) * Corticosteroid therapy = 1mg / kg of equivalent prednisone for more than a month * Toxic shock due to a deep candidiasis in the admission in resuscitation * Congenital deficits of Th17 (cutanéo-mucous candidiasis chronicles, syndrome of hyper IgE)