CompletedNot Applicable

The Influence of Running to ACL Deficiency

China60 participantsStarted 2017-04-26

Plain-language summary

The aim of this study is to investigate the influence of running to kinematic parameters of patients with anterior cruciate ligament.

Who can participate

Age range

20 Years – 30 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. 20\< age \< 30.
. Body mass index \< 30.
. For controls, no history of major injury or surgery in lower limbs; no symptoms of lower limbs; physical examination to test the lower limbs to be healthy.
. For ACLD group, history of knee injury for at least 2 weeks and able to walk and run; confirmed to be unilateral ACL injury by MRI; knee pain in the knee (ACL injury).
. The habit of moderate exercise (e.g. Jogging) at least once a week for at least 30 minutes.

Exclusion criteria

. Body mass index \>30.
. For controls, injury or surgery in hip/knee/ankle.
. For ACLD group, injury or surgery in hip/ankle; confirmed to be no ACL injury by arthroscopy.
. Neuropathic disease.
. Muscular disease.
. Lack ability to finish the procedure physically or mentally.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Knee flexion/extension angle at initial contact during gait.

Timeframe: 1 Day

Knee internal/external rotation angle at initial contact during gait.

Timeframe: 1 Day

Knee adduction/abduction angle at initial contact during gait.

Timeframe: 1 Day

Knee anterior/posterior translation at initial contact during gait.

Timeframe: 1 Day

Knee medial/lateral translation at initial contact during gait.

Timeframe: 1 Day

Knee proximal/distal translation at initial contact during gait.

Timeframe: 1 Day

Knee flexion/extension angle at opposite toe off during gait.

Timeframe: 1 Day

Trial details

NCT IDNCT03135600

SponsorGuangzhou General Hospital of Guangzhou Military Command

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2017-05-17

View on ClinicalTrials.gov More ACL Injury trials

Who can participate

Age range

20 Years – 30 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. 20\< age \< 30.
. Body mass index \< 30.
. For controls, no history of major injury or surgery in lower limbs; no symptoms of lower limbs; physical examination to test the lower limbs to be healthy.
. For ACLD group, history of knee injury for at least 2 weeks and able to walk and run; confirmed to be unilateral ACL injury by MRI; knee pain in the knee (ACL injury).
. The habit of moderate exercise (e.g. Jogging) at least once a week for at least 30 minutes.

Exclusion criteria

. Body mass index \>30.
. For controls, injury or surgery in hip/knee/ankle.
. For ACLD group, injury or surgery in hip/ankle; confirmed to be no ACL injury by arthroscopy.
. Neuropathic disease.
. Muscular disease.
. Lack ability to finish the procedure physically or mentally.

What they're measuring

Knee flexion/extension angle at initial contact during gait.

Timeframe: 1 Day

Knee internal/external rotation angle at initial contact during gait.

Timeframe: 1 Day

Knee adduction/abduction angle at initial contact during gait.

Timeframe: 1 Day

Knee anterior/posterior translation at initial contact during gait.

Timeframe: 1 Day

Knee medial/lateral translation at initial contact during gait.

Timeframe: 1 Day

Knee proximal/distal translation at initial contact during gait.

Timeframe: 1 Day

Knee flexion/extension angle at opposite toe off during gait.

Timeframe: 1 Day