UnknownNot Applicable

Desensitization of Nociceptive Afferents by Application of Topical Capsaicin, Trans-cinnamaldehyde and L-menthol

Denmark22 participantsStarted 2017-04

Plain-language summary

The purpose of this study is to investigate the potential desensitising effects of repeated applications of capsaicin, trans-cinnamaldehyde and L-menthol on thermal, mechanical and chemical sensory stimulations.

Who can participate

Age range18 Years – 60 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Healthy * Speaks and understands English or Danish * 18-60 years Exclusion Criteria: * Pregnancy or lactation * Drug addiction * Previous or current dermatological, neurological, musculoskeletal or mental illnesses * Lack of ability to cooperate * Current use of medications that may affect the trial

What they're measuring

Cold Pain Threshold (CPT)

Timeframe: Assessed at 5 visits on 5 consecutive days

Heat Pain Threshold (HPT)

Timeframe: Assessed at 5 visits on 5 consecutive days

Trial details

NCT IDNCT03132142

SponsorAalborg University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2017-08

Contact for this trial

Lars Arendt-Nielsen, Professor

0045 99408830 lan@hst.aau.dk

View on ClinicalTrials.gov More Pain trials