Pulse Pressure Variability With Position Before EPIdural Analgesia (NCT03126136) | Clinical Trial Compass
CompletedNot Applicable
Pulse Pressure Variability With Position Before EPIdural Analgesia
France1 participantsStarted 2018-12-12
Plain-language summary
Fetal heart rate abnormalities are common. Miller et al. have demonstrated that new onset fetal heart rate abnormalities after initial labor epidural dosing occur more frequently in women with a low admission pulse pressure than those with a normal admission pulse. The aim of the present study is to look for a statistical link between the occurrence of a fetal heart abnormality requiring an intervention and maternal hemodynamic factors (blood pressure, pulse pressure, and cardiac output) measured before epidural analgesia in two positions: dorsal decubitus position and in the left lateral decubitus.
Who can participate
Age range
18 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* pregnant women
* gestational age ≥ 36 weeks
* single eutrophic fetus
* wishing for epidural analgesia
* cervical dilatation less than or equal to 5 cm
* spontaneous labor
* scheduled for a vaginal delivery.
Non-inclusion Criteria:
* prematurity (\< 36 weeks of amenorrhea) or post-term birth
* intention of induction of labour using oxytocin before epidural analgesia or prostaglandin
* contraindication to epidural analgesia
* history of hypertension or gravidic hypertension or heart disorder
* gestational diabetes
* foetal malformation or oligohydramnios or fetal growth abnormality
* fœtal macrosomia diagnosed by ultrasonic scanning
* hematocrit less than 20%
Exclusion Criteria
* induction of labour using oxytocin before epidural analgesia
* newborn weight \> 4kg at birth
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.