CompletedNot Applicable

Comparison of Duodenal Stenting vs Transpyloric and Duodenal Stenting for Malignant Obstruction

United States17 participantsStarted 2017-05-27

Plain-language summary

Malignant duodenal obstruction in patients not fit for surgery is treated by placing enteral stents during endoscopy. These patients may also have poor gastric motility. Hence bridging the pyloric opening with the stent along with the duodenal obstruction may deliver better symptomatic improvement. Both approaches are commonly clinically practiced but no formal comparative studies have been done to compare which one is better.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: 1 - Confirmed diagnosis of cancer 2\. Evidence of a single small bowel obstruction 3\. Considered palliative (can be on narcotics, chemotherapy, and/or radiation therapy) 4\. Not a surgical candidate 5\. \>18 years of age 6\. Able to give consent 7\. Eligible for endoscopy (medically fit) 8\. Able to traverse past obstruction with a guidewire Exclusion Criteria: 1 - \<18 years of age 2\. Unable to give consent 3\. Pregnant 4\. Have evidence of multiple sites of obstruction in the small bowel 5\. Have evidence of duodenal obstruction secondary to gastric cancer 6\. Ineligible for endoscopy (due to comorbidities or acuity of illness) 7\. Unable to traverse past obstruction with a guidewire

What they're measuring

Number of Participants With Any Change (2 Point Increase or Decrease) in Symptoms From Baseline

Timeframe: Baseline (before stent) and follow-up (after stent) at 48 hrs (including gastric emptying study) and then symptom follow up at each clinic/telephone visit up to 6 months.

Trial details

NCT IDNCT03125148

SponsorMedical College of Wisconsin

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2019-11-15

Results submitted2021-05-06