CompletedNot Applicable

The Validity of Central Venous to Arterial Co2 Difference During Living Donor Liver Transplantation

Egypt20 participantsStarted 2017-04-25

Plain-language summary

Study will be conducted on 20 patients ASA III-IV undergoing orthotopic liver transplantation. Blood samples will be obtained simultaneously from arterial line, pulmonary artery catheter and central venous catheter at 4 specific time points baseline, immediately after insertion of PAC; at the end of the dissection phase; 30 minutes after anhepatic phase; 30 minutes after unclamping. Blood samples will be also obtained whenever PPV is more than 15% and patient will need fluid therapy

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * ASA II to IV patients with end-stage liver disease * patients undergoing orthotopic living donor liver transplantation * age \> 18 years Exclusion Criteria: * acute fulminant liver failure * age \< 18 years

What they're measuring

correlation between the PPV(pulse pressure variation) and Pcv-a CO2 (central venous to arterial) gap

Timeframe: baseline 5 min after induction of anesthesia, immediately after insertion of PAC; 30 minutes after the dissection phase; 30 minutes after anhepatic phase; 30 minutes after unclamping

Trial details

NCT IDNCT03123172

SponsorKasr El Aini Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2017-07-15

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