CompletedNot Applicable

Comparison of Opioid Based and Opioid Free Anaesthesia in Transsphenoidal Surgery

India60 participantsStarted 2017-01

Plain-language summary

This study has been planned to compare the effect of opioid free anaesthesia using dexmedetomidine and ketamine with opioid based anaesthesia using fentanyl in maintaining the intraoperative hemodynamic stability and recovery characteristics in patients undergoing Transsphenoidal surgery of pituitary tumors.

Who can participate

Age range18 Years – 65 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * patients suffering significant pituitary adenocarcinomas posted for transsphenoidal resection of tumor * age group between 18 to 65 yr * Both males and females * ASA physical status 1 to 2 Exclusion Criteria: * pts taking opioid for chronic pain * Pregnant or nursing woman * Preoperative GCS \<15 * HR\<50/min * Patients with allergies to study medication * Patients with psychiatric disorder * Patients with unstable cardiorespiratory disorder * Patients with hepatic and renal insufficiency

What they're measuring

To measure the emerence and extubation times in both groups

Timeframe: 15minutes

to measure the level of emergence in both the groups

Timeframe: 15min

to measure the level of cognition in both the groups

Timeframe: 15min

Trial details

NCT IDNCT03120234

SponsorPost Graduate Institute of Medical Education and Research, Chandigarh

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2017-10

View on ClinicalTrials.gov More Opioid Free Anaesthesia trials