TerminatedNot Applicable

ACCESS to the Cardiac Cath Lab in Patients Without STEMI Resuscitated From Out-of-hospital VT/VF Cardiac Arrest

Stopped: Low enrollment, funding withdrawn

United States, Canada65 participantsStarted 2017-12-12

Plain-language summary

To determine if survival to hospital discharge with good neurological outcome for adults ages 18-75 who are resuscitated from out-of-hospital VT/VF cardiac arrest without clinical signs of a heart attack do better by going straight to the cardiac catheterization laboratory or admitted to the intensive care unit for evaluation. The investigators think a large portion of resuscitated patients presenting with VT/VF have ischemic heart disease which is the cause for the arrest. And prompt access to the cardiac catheterization laboratory to reverse the blocked artery will improve survival with good neurological outcomes.

Who can participate

Age range

18 Years – 75 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Adult presumed or known to be 18-75 years old * Resuscitated from OOHCA * Initial cardiac arrest rhythm of pulseless VT/VF (including patients treated with an AED) * No ST-segment elevation MI (No STEMI) (or STEMI-equivalent syndrome) on ED 12-lead ECG (as interpreted by a physician) Exclusion Criteria: * Initial non-shockable out-of-hospital cardiac arrest rhythm (pulseless electrical activity or asystole) * Valid do not resuscitate orders (DNR), * Blunt, penetrating, or burn-related injury, drowning, electrocution or known overdose, * Known prisoners * Known pregnancy, * ST-segment elevation on ED 12-lead ECG (as interpreted by a physician) * Absolute contraindications to emergent coronary angiography including, * known anaphylactic reaction to angiographic contrast media, * active gastrointestinal or internal bleeding, or * severe concomitant illness that drastically shortens life expectancy or increases risk of the procedure. * Suspected or confirmed intracranial bleeding * Refractory cardiac arrest (prior to randomization) * Patients meeting ACCESS Trial eligibility criteria initially seen in an outside hospital and then transferred to an ACCESS Trial participating hospital

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Survival to Hospital Discharge With mRS ≤ 3

Timeframe: Up to 3 weeks

Trial details

NCT IDNCT03119571

SponsorUniversity of Minnesota

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2019-11-26

Results submitted2020-11-25

View on ClinicalTrials.gov More Cardiac Arrest Due to Underlying Cardiac Condition trials