CompletedPhase 4

Project PROTECT: Protecting Nursing Homes From Infections and Hospitalization

United States13,952 participantsStarted 2017-04-03

Plain-language summary

This is a cluster-randomized trial of nursing homes to assess whether decolonization with routine chlorhexidine bathing and periodic use of nasal antiseptics can reduce hospitalizations associated with infections, antibiotic utilization, and multi-drug resistant organism (MDRO) prevalence. The comparator arm will be routine bathing care.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria Nursing homes will be eligible to participate if they meet the following criteria: * Licensed nursing home in Orange County or Southern Los Angeles County serving adults * Minimal use of chlorhexidine bathing\* * Minimal use of nasal decolonization\* \*Minimal use defined as \<15% of residents receiving at least one chlorhexidine bath or nasal decolonization treatment during their nursing home stay. Exclusion Criteria Nursing homes will not be eligible to participate if they meet the following criteria: * Facilities routinely using decolonization * Dedicated psychiatric nursing homes * Facilities with a resident population with \>=20% combative patients * Pediatric facilities Note: in any participating nursing home, residents with active end-of-life comfort care only measures are excluded

What they're measuring

Hospital Transfers Due to Infection

Timeframe: 18 months

Trial details

NCT IDNCT03118232

SponsorUniversity of California, Irvine

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-10-10

Results submitted2023-11-09

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