The main purpose of this study is to evaluate the effects of melatonin in the regulation of the vascular injury in patients under carotid endarterectomy through population-based, randomized, double-blind, placebo-controlled trial.
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Melatonin effects on patients under CEA assessed by the concentration of SOD
Timeframe: 3 months
Melatonin effects on patients under CEA assessed by the concentration of MDA
Timeframe: 3 months
Melatonin effects on patients under CEA assessed by the concentration of S100b
Timeframe: 3 months
Melatonin effects on patients under CEA assessed by the concentration of eNOS
Timeframe: 3 months
Melatonin effects on patients under CEA assessed by the concentration of Nrf-2
Timeframe: 3 months
Melatonin effects on patients under CEA assessed by the concentration of IL-6
Timeframe: 3 months
Melatonin effects on patients under CEA assessed by the concentration of NF-κB p65
Timeframe: 3 months