Efficacy of Platelet-rich Plasma (PRP) in the Treatment of Dark Circles Under the Eyes

Inclusion Criteria: * Patients with periorbital hyperpigmentation Exclusion Criteria: * patients with known platelet dysfunction syndrome * patients with platelet count less than 100,000 ul * patient with hemodynamic instability * patients with severe systemic illness or malignancy or chronic medical illness (e.g. diabetes, chronic infections, and blood dyscrasias). * patients with local skin disorders or active herpes infection at the site of the procedure. * patients on anti-coagulants therapy or non-steroidal anti-inflammatory drugs (NSAID) within 48 hours of procedure, * patients with corticosteroid injection at treatment site within 1 month, systemic use of corticosteroids within 2 weeks * patients with recent fever or illness, and hemoglobin level\< 10 g/dl. * pregnancy * history of keloidal scarring.