CompletedNot Applicable

Comparing the Efficacy of Epidural and Quadratus Lumborum Analgesia After Open Nephrectomy Surgery

United States57 participantsStarted 2018-05-01

Plain-language summary

This study aims to assess if Quadratus Lumborum (QL) blocks are non-inferior to epidural analgesia for pain control and opioid consumption through the third postoperative day in patients having open partial nephrectomy. Patients satisfying all inclusion and exclusion criteria will be randomized in a 1:1 ratio to either epidural catheter or QL catheter.

Who can participate

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: Adults having for open unilateral partial nephrectomy surgery. Exclusion Criteria: 1\. Pregnancy 2. Intolerance or allergy to opioids 3. Previous radical nephrectomy surgery/midline incision 4. Contraindication to epidural analgesia 5. Contraindications to QL block 6. Chronic pain characterized by: i.Opioids use for more than 30 consecutive days within the 3 preoperative months at the dose equal or greater than equivalent of 15 mg of morphine ii.Abdominal pain for more than 6 months, present most days of the week-

What they're measuring

Total opioid consumption

Timeframe: Arrival to post anesthesia care unit until 72 hours after surgery

Postoperative pain

Timeframe: Arrival to post anesthesia care unit until 72 hours after surgery

Trial details

NCT IDNCT03110081

SponsorThe Cleveland Clinic

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2020-09-14

View on ClinicalTrials.gov More Open Nephrectomy Surgery trials