CompletedNot Applicable

Evaluation of Fetal Cardiac Function and Vascular Hemodynamics in Intrauterine Growth Restriction

Egypt534 participantsStarted 2017-05-10

Plain-language summary

Intrauterine growth restriction (IUGR) is one of the major contributors to perinatal mortality and morbidity and is characterized by complex hemodynamic changes involving placental and fetal arterial, cardiac and venous circulations .However, the temporal sequence of these modifications in relation to other hemodynamic changes of the fetal arterial and venous circulations is unknown. The aim of this study was to evaluate cardiac function and other hemodynamic changes in a group of fetuses with IUGR and clinical impact on perinatal outcome .

Who can participate

Age range18 Years – 40 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Singleton fetus with normal fetal anatomy documented a detailed sonogram. * Fetal abdominal circumference \<5th percentile for gestational age. * Evidence of placental insufficiency documented by an elevated umbilical artery pulsatility index (UA-PI) by reference ranges. Exclusion Criteria: * evidence of fetal infection * chorioamnionitis * fetal anomalies * abnormal fetal karyotype * patient withdrawal from the study and/or unavailability for follow-up.

What they're measuring

Myocardial performance index

Timeframe: 5 minutes

Aortic isthmus flow index

Timeframe: 5 minutes

Cerebroplacental ratio

Timeframe: 5 minutes

Preload Index in inferior vena cava

Timeframe: 5 minutes

Trial details

NCT IDNCT03108040

SponsorAssiut University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2019-07-10

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