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Epicardial Ablation in Brugada Syndrome. An Extension Study of 500 BrS.Patients

Italy300 participantsStarted 2017-03-14

Plain-language summary

This study represents an extension of a previous study (NCT02641431) on the acute and long-term benefit of epicardial ablation on elimination of both BrS-ECG pattern and VT/VF inducibility in 500 consecutive BrS patients.

Who can participate

Age range18 Years – 80 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Symptomatic BrS patients with typical BrS-related symptoms (cardiac arrest or syncope) or without typical BrS-related symptoms (dizziness, palpitations, presyncope, dyspnea) ICD implantation, spontaneous or ajmaline-induced type 1 Br pattern. Exclusion Criteria: * Age \< 18 years, prior epicardial ablation, pregnancy, co-morbidities.

What they're measuring

Type 1 BrS-ECG pattern elimination by epicardial ablation before and after ajmaline test.

Timeframe: 1 day after ablation

VT/VF inducibility

Timeframe: immediately after mapping and ablation

Absence of VT/VF

Timeframe: 1,3,6,12,18,24,36,48,60,72,84,96,108,120 months after ablation

Trial details

NCT IDNCT03106701

SponsorIRCCS Policlinico S. Donato

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-09-28

Contact for this trial

Carlo Pappone, MD

+39 02 52774260 carlo.pappone@af-ablation.org

View on ClinicalTrials.gov More ECG Brugada Pattern trials