In the field of dermatology the healing process and therefore the success of a laser treatment are strongly determined by an appropriate postoperative treatment of the laser-treated skin. The manufacturer of CO2 laser systems recommends the application of Vaseline postoperatively to protect the treated tissue from air exposition until encrustation of the laser-treated skin decreases (usually after 7-14 days). An alternative to Vaseline could be Bepanthen® "Wund- und Heilsalbe" (Bayer). It contains the active ingredient pro-vitamin Dexapanthenol, which is widely used in dermatology therapy. The product helps to stabilize the protective barrier of the skin, to reduce the skin irritation, to stimulate the skin regeneration and to promote the wound healing. In an in-vitro study Bepanthen® "Wund- und Heilsalbe" triggered wound closure significantly faster compared to Vaseline. In this study the effect of Bepanthen® "Wund- und Heilsalbe" on wound healing should be investigated and compared to Vaseline in vivo following fractional ablative CO2 laser treatment of photo-damaged skin.
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Change of the diameter of the individual lesions [initial value 1.3mm] between study visits.
Timeframe: Over 2 weeks (immediately after laser treatment and on day 1, 2, 5 and 14 after laser treatment)
Change of the size of the individual lesions between study visits.
Timeframe: Over 2 weeks (immediately after laser treatment and on day 1, 2, 5 and 14 after laser treatment)
Visual changes of the wound healing between study visits.
Timeframe: Over 2 weeks (immediately after laser treatment and on day 1, 2, 5 and 14 after laser treatment)
Change of the wound under cosmetic aspects between study visits.
Timeframe: Over 2 weeks (immediately after laser treatment and on day 1, 2, 5 and 14 after laser treatment)