CompletedNot Applicable

TIVA and VIMA on Blood Glucose and Insulin Levels in Lung Lobectomy Patients

South Korea60 participantsStarted 2017-04-03

Plain-language summary

The purpose of this study was to evaluate the efficacy and safety of sevoflurane-only Volatile induction and maintenance anesthesia (VIMA) and total intravenous anesthesia (TIVA) using only propofol in adult patients scheduled for elective lobectomy surgery. We would like to know if there is a difference in blood glucose levels during surgery and whether the cause is due to the difference in secretion of insulin and cortisol. In addition, we aim to contribute to the improvement of the prognosis of the patients by helping the selection of general anesthesia more effective in maintaining homeostasis in the surgical patients by general anesthesia and further controlling the blood glucose level.

Who can participate

Age range18 Years – 75 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Non-diabetic patients American Society of Anesthesiologist Physical Status Classification 1 - 3 Exclusion Criteria: * Diabetes mellitus or glucose intolerance patients, patients with adrenocortical hormone metabolism abnormality, patients with steroids therapy within the last month, patients with liver disease (aspartate aminotransferase\> 40 IU / L or alanine aminotransferase\> 40 IU / L), patients with kidney disease (creatinine 1.5 mg / dl), pregnant woman, patients with hypersensitivity to anesthetics used in research, patients who required ventilator care after surgery

What they're measuring

Perioperative glucose level

Timeframe: up to 1 hour after surgery

Trial details

NCT IDNCT03094533

SponsorYeungnam University College of Medicine

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2018-10-31

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