CompletedNot Applicable

Acute Effects of DC7-2, a Meat Derived Octapeptide, on Appetite

Denmark32 participantsStarted 2017-08-21

Plain-language summary

A double-blind, randomized crossover design with four arms including three experimental conditions and placebo will be applied. After having successfully completed screening procedures, eligible participants will be invited to four separate test days. The test days are separated with at least 7 days, however 4 days can be accepted for logistical reasons. During the entire course of the study, participants must remain weight stable and not change their diet or physical activity level. Significant changes in diet, physical activity level (evaluated by the sub-investigator) or weight change ±3 kg over the course of the study (from screening to completion of the last test day) results in exclusion of that subject.

Who can participate

Age range18 Years – 65 Years

SexMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Healthy men * Age between 18 and 65 years * BMI between 27-35 kg/m2 Exclusion Criteria: * Vegetarians * Participants unable to consume or known to get nausea from consuming capsules * Participants not able to comply with the study protocol, including consumption of the specific study foods (pictures of study foods shown at screening) * Any known food allergies or food intolerance likely to affect the present study * Weight change of ±3 kg two months prior to the study * Vigorous physical activity more than 5 hours/week * Alcohol intake above the recommendations from the Danish Health and Medicines Authority (\>14 units/week) * Substance abuse * Smoking, smoking cessation within the past 3 months or nicotine use (electronic cigarettes, gum etc.). Irregular smokers accepted * Use currently or within the previous 3 months of any medication or supplements known to affect appetite or body weight as judged by the investigators * Chronic diseases (e.g. cancer, thyroid disease, heart disease, diabetes, neurological disorders, or sleep disorders) or other relevant health problems as judged by the investigators * Simultaneous or within the past month participation in other clinical studies * Participant's general condition contraindicates participating in the study, as judged by the investigators or the medical expert

What they're measuring

Energy intake

Timeframe: 360 min

Trial details

NCT IDNCT03089190

SponsorArne Astrup

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2017-12-07