Proliposomal Intravesical Paclitaxel for Treatment of Low-Grade, Stage Ta, Non Muscle Invasive Bladder Cancer

Inclusion Criteria: * Has a diagnosis of low grade (G1 or G2), uni- or multifocal papillary appearing bladder tumor, stage Ta. * For part 1, subject will have ≥ 1 and ≤ 5 tumors (prior to TURBT), none of which exceeds 3.0 cm in diameter; for part 2, patient will have ≥ 2 and ≤ 5 tumors (prior to TURBT), none of which exceeds 3.0 cm in diameter (resection loop \~1 cm), OR, for part 2, subject meets this inclusion if on cystoscopic assessment they have a solitary papillary tumor (\> 0.5 cm and ≤ 2.0 cm in diameter).. * Subject is surgical candidate for TURBT as part of normal NMIBC treatment plan. For part 1, successful completion of TURBT procedure. For part 2, successful completion of cystoscopic assessment/TURBT procedure with one marker lesion left intact; the marker lesion should be \> 0.5 cm and \< 2.0 cm in diameter. * Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1. * Peripheral neuropathy grade 1 or less. * Adequate hematological, hepatic, and renal parameters; i.e., hemoglobin \> 10 g/dL, creatinine \< 3.5 mg/dL, bilirubin \< 1.5 mg/dL , and aspartate aminotransferase, alanine aminotransferase \< 50 U/L, and alkaline phosphatase \< 130 U/L. * All sexually active subjects of reproductive potential are required to use or start using a reliable method of birth control at least 2 weeks prior to study enrollment, throughout the study, and for at least 3 months following completion of study therapy. * Females of childbearing potential must have a neg…