CompletedNot Applicable

Gingival Bleeding and Von Willebrand Disease Typ 2 and 3

Germany48 participantsStarted 2015-07-16

Plain-language summary

Von Willebrand disease (VWD) is the most common inherent bleeding disorder resulting in prolonged bleeding time. Gingival bleeding is a frequently reported symptom of VWD. However, gingival bleeding is also known as a leading symptom of plaque-induced gingivitis and untreated periodontal disease. Gingival bleeding in VWD patients may be triggered by gingival inflammation and not a genuine symptom. Thus, this study evaluates whether type 2 and 3 VWD determines an increased susceptibility to gingival bleeding in response to the oral biofilm.

Who can participate

Age range18 Years – 80 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria von Willebrand Patients: * 18 - 80 years old * no other bleeding disorder except 2 and 3 von Willebrand disease Inclusion Criteria healthy controls: * no bleeding disorder * no anticoagulative medication Exclusion Criteria von Willebrand Patients: \- requirement of systemic antibiotics for measures that may cause transitory bacteraemia Exclusion Criteria healthy controls: \- bleeding disorder

What they're measuring

Bleeding on Probing (BOP)

Timeframe: cross-sectional: only one assessment at the time of examination

Trial details

NCT IDNCT03078595

SponsorGoethe University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2017-04-04

Results submitted2019-08-08

View on ClinicalTrials.gov More Gingival Bleeding trials