CompletedNot Applicable

Proposal for Intraoperative Administration of Intravenous Indocyanine Green to Evaluate Position of the Optic Canal, Position of the Internal Carotid Arteries, Tumor Vascularization, and Vessel Encasement in Endoscopic Endonasal Cranial Base Surgery

United States23 participantsStarted 2017-11-06

Plain-language summary

This study is being done to demonstrate the feasibility of using a nasal endoscope to perform intraoperative angiography of surgical field, with the goals to evaluate anatomical landmarks and tumor characteristics during skull base surgery and publish a technical note.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * 18 years and above * Patients undergoing an an EEA for cranial base pathology that will require any of the following will be eligible for the study: optic canal decompression, intradural tumor dissection, dissection of tumor around the internal carotid artery. Exclusion Criteria: * Less than 18 years of age * History of sulfa, iodide, or penicillin allergy * Previous anaphylactic reaction to ICG * Women currently pregnant or nursing

What they're measuring

ICG Fluorescence Ratio

Timeframe: Before intradural dissection and during tumor dissection.

Trial details

NCT IDNCT03072186

SponsorOhio State University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2019-01-15

Results submitted2020-05-05

View on ClinicalTrials.gov More Skull Base Neoplasms trials