CompletedPhase 4

Comparison of Obturator Nerve Blockade and Neuromuscular Blockade

United States60 participantsStarted 2017-04-25

Plain-language summary

Patients diagnosed with posterolateral bladder tumors will be invited to participate in the study. Subjects will be randomized to receive an ultrasound-guided obturator block or a neuromuscular blocking agent after the induction of general anesthesia in an attempt to block the obturator reflex during surgery.

Who can participate

Age range18 Years – 90 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients ≥ 18 years of age * Planned TURBT for unilateral or bilateral posterolateral bladder tumors * Ability to understand and provide informed consent Exclusion Criteria: * Patient refusal or inability to provide informed consent * True allergy, not sensitivity, to local anesthetics * True allergy, not sensitivity, Propofol * True allergy, not sensitivity, general anesthetic agents * Pregnancy * Severe hepatic impairment * Evidence of infection at or near the proposed needle insertion site * Any sensorimotor deficit of the lower extremity, whether acute or chronic * Inability to walk without assistance * Lower extremity joint replacement surgery in the preceding six months

What they're measuring

Number of Patients With Incidence of Intraoperative Adductor Spasm

Timeframe: intraoperative

Trial details

NCT IDNCT03063255

SponsorUniversity of Florida

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2019-09-19

Results submitted2020-09-14

View on ClinicalTrials.gov More Cancer of Bladder trials