By InvitationNot Applicable

Predicting Cardiometabolic Risk in Mild-to-Moderate Obstructive Sleep Apnea: Inflammation vs. Apnea/Hypopnea Index

United States196 participantsStarted 2017-03-01

Plain-language summary

The purpose of the study is to compare the relative contribution of systemic inflammation vs. Obstructive Sleep Apnea (OSA) severity (as measured by Apnea Hypopnea Index) in predicting cardiovascular and metabolic aberrations associated with mild-to-moderate obstructive sleep apnea.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Mild to moderate OSA (5≤ AHI \<30) * BMI ≤ 45 * Age ≥ 18 * Men \& Women Exclusion Criteria: * AHI ≥ 30 * BMI \>45 * Current use of steroids or anti-inflammatory medication * Diagnosis of insulin dependent diabetes * Diagnosis of autoimmune disorder * Shiftwork * Current use of CPAP

What they're measuring

Presence of the metabolic syndrome

Timeframe: baseline

Obstructive Sleep Apnea

Timeframe: baseline

Markers of systemic inflammation

Timeframe: baseline

Trial details

NCT IDNCT03062748

SponsorMilton S. Hershey Medical Center

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2027-12

View on ClinicalTrials.gov More Obstructive Sleep Apnea trials